Placental sulfatase deficiency prolonged pregnancy pdf

It may be associated with failed induction of labor and prolonged labor. Management of postterm pregnancy practice guidelines. Prolonged pregnancy is defined as lasting beyond 287 days, or 41 weeks, since the. Scribd is the worlds largest social reading and publishing site.

Placental sulfatase deficiency definition of placental. Since a postterm pregnancy is linked with both fetal and maternal health complications, doctors usually do everything they can to ensure that an infant is delivered as close to the due date as possible. Postterm pregnancy causes and risks birth injury guide. Due to the low estrogen levels, these pregnancies may be prolonged, with dysfunctional labor that may end in cesarean delivery. Placental sulfatase deficiency placental sulfatase deficiency is a rare x. Postterm pregnancy is a pregnancy that lasts longer than 42 weeks. Postmature is reserved for the pathologic syndrome in which the fetus experiences placental insufficiency and resultant iugr. Placental sulphatase deficiency for example, is a rare xlinked recessive. Definition postterm pregnancy, prolonged pregnancy. A pregnancy with placental sulfatase deficiency was suspected when a 36yearold patient at 41 weeks of gestation was found to have extremely low uri. Post term pregnancy is associated with an increased risk of fetal and neonatal. Sulfatase deficiency is probably a congenital, sexspecific, xlinked placental enzyme defect.

Maternal obesity, length of gestation, risk of postdates pregnancy and spontaneous onset of labour at term. The other case reports mostly concern patients associated with a prolonged pregnancy, lack of cervical dilatation, or absent induction of labor. Prolonged pregnancy is considered highrisk as the post term fetus has an. Placental sulfatase deficiency placental sulfatase deficiency is a rare xlinked recessive. Placental sulfatase deficiency and congenital ichthyosis with. Longterm effects of radioiodine in toxic multinodular goitre. Placental sulfatase deficiency, fetal anencephaly, and male sex have been associated with prolongation of pregnancy, and genetic predisposition also may play a role. Rarely, postterm pregnancy may be associated with placental sulfatase deficiency or fetal anencephaly. Some fetal malformations, such as anencephaly or fetal adrenal hyperplasia, have been associated with prolonged pregnancy.

Male sex also has been associated with prolongation of pregnancy 6. Acog releases guidelines on management of postterm pregnancy. Genetic predisposition may play a role in prolonging pregnancy 5, 7. Placental sulphatase deficiency for example, is a rare xlinked recessive disorder that can prevent spontaneous labour due to a defect in placental sulphatase.

Pdf placental steroid sulphatase deficiency ssd is an xlinked inborn error. That is two weeks past the normal 40week gestation period. Identified risk factors include increasing maternal age, obesity, nulliparity, prior postterm delivery, male fetal sex, placental sulfatase deficiency and fetal anecephaly 1, 345. Development of ichthyosis in male infants at 2 to 3. Guidelines for the management of postterm pregnancy.